Clinical Outcomes of Surgical Management of Liver Abscess: A Systematic Review

Haneen I Brnawi; Abdullah  Mohammed A AL Madshush; Tariq  Majed M Alali; Mohammed I. Altidlawi; Raghad  Hamdan A Albalawi; Abdullah  Hisham M Khoja; Meshary  Defallah G Alzahrani; Nouf  Yousef A Alharbi; Yasser  Saadi M Alzahrani; Rahaf  Hamdan A Albalawi; Bandr  Mohammed F Alenzi; Anfal  Salem J Alhawiti; Rawan  Hussain Q Albalawi

doi:10.54293/smhj.v4i1.92

Authors

Haneen I Brnawi Consultant general surgery and assistant professor in Tabuk University, Tabuk, KSA.
Abdullah Mohammed A AL Madshush Student, Faculty of Medicine, Tabuk University, Tabuk, KSA. https://orcid.org/0000-0002-8812-1725
Tariq Majed M Alali Student, Faculty of Medicine, Tabuk University, Tabuk, KSA. https://orcid.org/0009-0006-3557-8285
Mohammed I. Altidlawi Student, Faculty of Medicine, Tabuk University, Tabuk, KSA.
Raghad Hamdan A Albalawi Student, Faculty of Medicine, Tabuk University, Tabuk, KSA.
Abdullah Hisham M Khoja Student, Faculty of Medicine, Tabuk University, Tabuk, KSA. https://orcid.org/0009-0001-3777-5470
Meshary Defallah G Alzahrani Student, Faculty of Medicine, Tabuk University, Tabuk, KSA.
Nouf Yousef A Alharbi Student, Faculty of Medicine, Tabuk University, Tabuk, KSA. https://orcid.org/0009-0006-4079-9461
Yasser Saadi M Alzahrani Student, Faculty of Medicine, Tabuk University, Tabuk, KSA. https://orcid.org/0009-0008-8436-3154
Rahaf Hamdan A Albalawi Student, Faculty of Medicine, Tabuk University, Tabuk, KSA.
Bandr Mohammed F Alenzi Student, Faculty of Medicine, Tabuk University, Tabuk, KSA.
Anfal Salem J Alhawiti Student, Faculty of Medicine, Tabuk University, Tabuk, KSA.
Rawan Hussain Q Albalawi Student, Faculty of Medicine, Tabuk University, Tabuk, KSA.

DOI:

https://doi.org/10.54293/smhj.v4i1.92

Keywords:

Liver abscess, Management, Open Surgery, Laparascopy, Systematic review

Abstract

Background: Treatment for liver abscess, a major source of intra-abdominal infection, depends on how it presents. Over time, the method of treating PLA has changed, moving from open surgical drainage to percutaneous drainage assisted by imaging.

Objectives: This systematic review aims to investigate the efficacy of surgical approaches to manage liver abscesses.

Methods: PubMed, SCOPUS, Web of Science, and Science Direct, were systematically searched to include the relevant literature. Rayyan QRCI was used throughout this systematic approach.

Results & interpretation: included nine studies with a total of 632 patients. Antibiotics and/ or US or CT-guided PNA are the first line of treatment to manage liver abscesses. However, the relatively few individuals in whom aspiration was impossible because of thick pus, a septated or loculated abscess, or an abscess that had ruptured in any body cavity were indications for open or laparoscopic surgery. Additionally, we demonstrated that successful surgical procedures were linked to a significant decrease in mortality and a shorter hospital stay in patients with ruptured ALA. Only generalized peritonitis or further infections refractory to non-surgical treatment necessitate surgery. Additional randomized controlled studies involving a suitable patient population should be conducted to raise the level of evidence.