Overview of Nephrotic Syndrome in Arab Children:  Systematic review

Amir Fayyaz Shaikh Sardar Muhammad; Fawaz  jamal H Alanezi; Ibrahim Muqbil W Alanazi; Badar  Shabikan M Alanazi; Abdullah  khalil A Alanazi; Yuosef  hadi alenezi; Khalid  saleh mobark Almarjan; Eissa  Zaedan M Alenezi; Ibrahim  Awadh R Alanazi; Malek Ramadan Alenezi; Abdulrhman  subhi hindi alanazi; Ziyad  Yahya Ahmed Alzahrani; Naif  alsayed Alanazi

doi:10.54293/smhj.v4i1.96

Authors

Amir Fayyaz Shaikh Sardar Muhammad Pediatric consultant Maternity & Pediatric hospital of Arar, KSA.
Fawaz jamal H Alanezi Internal medicine senior registrar Maternity & Pediatric hospital of Arar, KSA.
Ibrahim Muqbil W Alanazi General practitioner Maternity & Pediatric hospital of Arar, KSA. https://orcid.org/0009-0004-7026-0403
Badar Shabikan M Alanazi Nursing technician Maternity & Pediatric hospital of Arar, KSA.
Abdullah khalil A Alanazi Nursing technician Maternity & Pediatric hospital of Arar, KSA.
Yuosef hadi alenezi Nursing technician Maternity & Pediatric hospital of Arar, KSA.
Khalid saleh mobark Almarjan General practitioner Maternity & Pediatric hospital of Arar, KSA.
Eissa Zaedan M Alenezi General practitioner, Maternity & Pediatric hospital of arar, KSA. https://orcid.org/0009-0009-0135-1949
Ibrahim Awadh R Alanazi Pediatric resident physician- General practitioner Maternity & Pediatric hospital of arar,KSA.
Malek Ramadan Alenezi Pediatric resident physician- General practitioner Prince Abdualziz bin Musaed hospital, Arar, KSA. https://orcid.org/0009-0001-2645-4110
Abdulrhman subhi hindi alanazi laboratory technician, North Medical Tower at Arar, KSA.
Ziyad Yahya Ahmed Alzahrani Public health specialist, North Medical Tower at Arar, KSA. https://orcid.org/0009-0009-7106-9797
Naif alsayed Alanazi laboratory technician Maternity & Pediatric hospital of arar , KSA.

DOI:

https://doi.org/10.54293/smhj.v4i1.96

Keywords:

Nephrotic syndrome; Incidence; infants; children; Systematic review.

Abstract

Background: Nephrotic syndrome (NS) is documented as a common chronic disease in childhood. Children with this illness repeatedly show periorbital swelling with or without generalized edema. It was estimated that the annual incidence rate of NS in children aged below 16 years is 2 to 7 new cases per 100 000, with a prevalence rate of 16 cases per 100 000.

Objectives: This systematic review comprehensively investigates the recently published literature on incidence and pattern of nephrotic syndrome in infants and children.

Methods: PubMed, SCOPUS, Web of Science, Science Direct, and Google Scholar were systematically searched for relevant literature. Rayyan QRCI was employed throughout this comprehensive process.

Results & interpretation: This review included nine studies with a total of 1418 patients. The incidence, mean age, sex dominance in different sample groups and the histopathological patterns were differ according to many factors.